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Longevity drug, not for weight loss; leveraging cardiovascular, metabolic, and anti-aging benefits

"I use a GLP-1 drug. I don't use it for weight loss — I've been on my fighting weight for a while. My percent body fat is substantially healthy because I work out and I'm very careful about what I eat. I use it as a longevity drug because of all the benefits..."

Peter Diamandis

Weight management for obese individuals; potential longevity benefits including brain health and immune function

"In general, I'm very favorable. If you're obese, it's almost a must — go talk to your doctor. I think if you can't lose weight alone, please consider using these. I think obesity is the fastest way to an early grave. It's as close to a longevity drug as we ..."

David Sinclair

Bridge therapy for treatment-resistant depression and acute suicidality; rapidly dissipates suicidal risk while a longer-term treatment solution is found

"In my experience, I've used it sort of as a bridge to finding the solution for that patient rather than it being the solution. Occasionally it is the solution and the patient goes into remission from their depression, but more often than not in my experienc..."

Linus Abrams

"I'm very often sending my patients to go get ketamine with our friend Dave Rabin and others that are out there that are really good at creating a huge neuroplastic response."

Scott Sherr

"If I take metformin or the natural equivalent which is berberine... Taking it every other day, I think is better."

David Sinclair

"The doctor in Bloomington just put me on metformin. If it was up to me, I'd put the entire United States on metformin and a statin because the fucking food we eat is terrible."

John Mellencamp

Part of his anti-aging protocol, taken once every two weeks

"Some pills I take every day, sometimes I take them twice a day, sometimes I take once every two weeks, for example rapamycin. So each pill has a different frequency and a different protocol."

Bryan Johnson