Explore pharmacology

"If I take metformin or the natural equivalent which is berberine... Taking it every other day, I think is better."

David Sinclair

"The doctor in Bloomington just put me on metformin. If it was up to me, I'd put the entire United States on metformin and a statin because the fucking food we eat is terrible."

John Mellencamp

Cholesterol management with credible evidence base

"I take statins, I take ezetimibe, various interventions where there's very credible evidence that they move the needle."

Steve Horvath

"I've actually been on a statin to lower my LDL since I was 30... I insisted with my doctor initially with statins."

David Sinclair

Prostate health, increasing androgen receptor density, reducing nocturia to improve sleep and growth hormone/testosterone optimization, mild blood pressure reduction

"Tadalafil is a very underrated medication. It increases the density of the androgen receptor similarly to L-carnitine. Another benefit is that if you give it to people with nocturia, which is urinating at night in general, it will cut the episodes in half, ..."

Kyle Gillett

Prostate health and brain vasodilation for men over 40

"Low dose, like 2.5 to 5 mg per day, is very helpful for perfusion of the prostate. And also, it causes vasodilation in the brain. Our chair of male sexual health and urology at Stanford, Mike Eisenberg, he came on the podcast and he said pretty much every m..."

Andrew Huberman

"I'm taking high-dose vitamin B3 or niacin... I'm taking half a gram. Some people take a gram. And that's one of the few things that's been known to bring down the levels of LP little A."

David Sinclair