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Making ChatPRD launch videos and general agent work

"And so even though I really love Opus 5.5 as a model and even though it does really good work, the performance is so slow and you really feel that in a personal agent."

Claire Vo

Main AI harness and model for his work

"If Duet becomes more robust after it exits research preview, I can see myself using it a lot because right now Claude is my main harness and model and this has a ton of memory about how I like to work."

Peter Yang

Building and training an AI agent

"Christopher and I were working on an agent that I've been working with ChatGPT on, and I was being pretty firm with it, 'cause you're trying to train your agent, right?"

Tony Robbins

Rewriting and updating an old academic dissertation with current information

"So I had ChatGPT rewrite her dissertation that she wrote 20-something years ago, but everything is now current... She was like, 'This is amazing. What AI is this?' And I'm like, 'It's ChatGPT.'"

a16z

Coding sessions where it helps flesh out specifications

"I don't know if you've done a Claude Code session recently, but often what I find is, you know, I say, 'I want this.' And it's like, 'Oh yes, and you probably want this, this, and this too.' And I'm like, 'Yeah, actually, you're right. I do want that.'"

Clark Barrett

Shipping production code by running 3-4 parallel sessions with implementer and tech-lead reviewer agents. He built a data lake auto-promotion feature in about 10 days instead of 6 months.

"I tell Claude to spin up command line sub agents because those maintain their persistent session over time. And so you can have it spin up these agents separately. You can actually run them from other sessions and so on. And that allows you to be much more ..."

Jad Naous

Accessing ultra-fast (1,200 tokens/sec) Cerebras-powered inference via Astra

"He got access to that 1,200 tokens per second Cerebras capability. You can now get it on Astra. You have to go through Codex to get it... If you go through Codex to get access to Astra, you can put it on crazy fast hyper mode or whatever it's called. It's i..."

Dave Blundin

Coding agent for building the app and SEO content

"It's honestly basic Claude or Codex. ... I use extensively Codex and Claude, and I have also local models that I utilize for myself."

Rasty Turek

Writing long-form articles, such as an 8,000-word piece

"I used it for writing all weekend and it is without a doubt my favorite new writing model. It beats Astra, which was my previous favorite. It definitely beats Claude. It has an incredibly good feel for structuring information and I used it all weekend to wr..."

Dan Shipper

Medical research and turning interview transcripts into newsletter posts

"I think really pleasantly surprised by how good Gemini 4 did at doing medical research, answering the questions that I had... for something like medical questions, I actually do want something that's super well researched. And that combined with its improve..."

Peter Yang

Connector that identifies her team and feeds data into sites

"I go to where the team is collaborating. I go to Slack a lot. I go to Notion a lot, Google Drive, Google Calendar."

Kath Korevec

Accessing AI agents for clients inside team chat

"I actually set up this kind of Slack-based AI agent for my clients all the time. It's a really, really good way of accessing your AI agents, and this is awesome to see OpenAI moving into this category and making the agents and dots accessible within Slack."

Liam Ottley

Source of team runbooks and guides for the incident command site

"I had it from Notion go through and pull in what are our runbooks and how do we respond, what are the guides, etc. So this will actually open up the runbooks and guides and things in Notion if I want to."

Kath Korevec

AI-controlled document creation and management via Codex and ChatGPT integrations

"I love using Notion, especially with the AI tools that we've already downloaded. AI is better at using Notion than it is at using Google Docs. It's better at using Notion than ClickUp, for example, because Notion actually made their tools so that AI is real..."

Riley Brown

Finding out what Twitter is saying about a topic

"Sometimes I'll just ask Grok, and Grok is famously a little bit more unhinged. And so if I really care about like what is Twitter saying about the thing, cuz Twitter has strong opinions on both sides of the political divide, I'll just ask Grok."

Ali Abdaal

Collecting screenshots and articles about places to eat in Japan, then generating an HTML file of places organized by neighborhood

"Now between my trips here, I have a bot. I have a Grok bot and I take screenshots and articles and I just give it to my bot. I used to write everything down in a book. Now I just give it to my bot and I say when I'm in Japan, make me an HTML file of all the..."

This Week in Startups

Sketching, iterating, and handing off designs; iterating on linear flows like paywalls on canvas

"Figma had a complete hold on the whole design industry, for good reasons. It's just a great tool. 80% of my day was spent in Figma, both sketching ideas, iterating on different approaches, and also refining and handing off designs, and I feel like that's ju..."

Sam Stephenson

UI design with bot-assisted frame editing, design token usage, and end-to-end screen generation

"As xAI we design in whatever tools we need. We use Figma, we use canvas-based tools, we have our own prototype environments. The designer bot connects through the Figma MCP through the connector, so it will be able to directly change frames and update the d..."

Peng Zheng

Running AI agents independently on local hardware for AI sovereignty

"OpenClaw is a vote on making agents that are independent. If you use OpenClaw with Neotron or Gemma, which is Google's open source product, you will be sovereign AI. In other words, the AI running on your Mac Studio with 256 gigs of RAM."

This Week in Startups

Powers Jim, Brex's AI recruiting employee; also powers Pedro's personal 'autopilot' life management system that ingests Slack, email, and meeting notes

"This is Jim. Jim is our OpenClaw recruiter. It runs on effectively like a three-stage pipeline. We do use OpenClaw for this but the harness doesn't really matter as much as just the skills. I have this system that I call autopilot and basically what it does..."

Pedro Franceschi

Bug tickets assigned to AI agents

"A product person will say, 'Oh, we found this bug,' and leave a Linear ticket. With Linear, you can assign work to a person, but you can also assign work to an agent."

Ras Mic

Issue tracking integrated into the software factory workflow; factory automatically opens Linear issues when tasks are kicked off

"We use Linear in addition to using Slack so that everything gets tracked. So the factory integrates not just with Slack, it opens an issue."

Zach Lloyd

Testing Opus 5 for knowledge work tasks; creating investor slide decks; everyday enterprise tasks

"I recommend trying it within Claude Cowork or within Claude Code. Anthropic is positioning Opus 5 as its everyday model for enterprises, knowledge workers, and developers, and the best way to test it would probably be in the home tab using Claude Cowork."

Riley Brown

Logging into carrier portals to download and ingest documents; automating a previously manual business process

"If you look at Claude Cowork, which came out two weeks ago, and the types of spreadsheets and models that they're creating — you're like, oh, this is actually like valuable, good work. We use this internally for simple things like logging into carrier porta..."

JD Ross

Accepting payments and managing subscriptions for the OnlyWaivers SaaS app

"It will use a Stripe API for payment. Connect Stripe. Replit already has my Stripe API. I can now accept payments."

Chris Koerner

Handling subscription monetization for apps built on Replit; abstracting payment setup complexity for non-technical builders

"We have this deep partnership with Stripe where we've abstracted away all of the complexity. The user doesn't have to go sign up for Stripe, do the KYC upfront, figure out what a plan is. All of that is taken care of — we set up a Stripe sandbox in the back..."

Amol Jain

Online shopping for general goods with reliable delivery and returns

"My personal revealed preference is I would almost always want it from Amazon because I trust it's going to get there. I know where to go to look to see if it's on its way. I know where to go to process a return if I want to do that."

Ben Thompson

Brand awareness marketing and retail distribution channel for a beverage CPG brand

"We were 100% on Amazon from day one, which was a decision we made as a board to do that. And it was such a good decision, but you don't make a lot of money on Amazon as a beverage. We saw it as a great marketing tactic for awareness because it's in so many ..."

Allison Ellsworth

Coding agents and AI-assisted development workflows internally at ClickHouse

"Our Anthropic spend is up 100 times from what it was at the beginning of the year. I sent an email to the company and the subject was 'the AI awakening' and I said I think we're moving too slowly and I'm not seeing the adoption of these coding applications ..."

Aaron Katz

Business logic automation, workflow automation, coding agents

"We're using OpenAI, using Anthropic. We're going to increasingly use open source models to save money... we don't today have a budget constraint on our Anthropic contract. I think we're spending like probably 5 million a year or something. Ramping pretty fa..."

Ryan Petersen

Running AI models locally with better performance

"I would actually recommend using Nvidia chips for running a lot of these models. It's much better performance."

Yolan Yan

AI training chips and compute infrastructure

"Nvidia remains our absolute priority partner. They have the Frontier chip. Our next big training run in the fall will be done on Rubin."

Sarah Friar

Running Salesforce headlessly as a backend CRM/data system without logging into the UI

"We run Salesforce headless. We don't even log into Salesforce — and these are opportunities and threats."

Jason Lemkin

Core CRM system of record for the firm, increasingly accessed via Claude MCP

"We use Salesforce a lot. We have a 20-year instance. We're deeply embedded in it. And more and more people are using it via Claude."

Rory O'Driscoll

Selling Bankroll Coffee online.

"What's funny is that Shopify actually sponsors quite a bit of our podcast. They're fantastic. It's how I sold Bankroll Coffee in the beginning."

Graham Stephan

Running an e-commerce store with dedicated sourcing, developer, and email agents managing product research and store operations

"I've got a separate Grok Bot account that I pay the $200 for because I'm so crazy about keeping the context separate and it's just Shopify. I'm training it to use the Shopify developer tools and to source products. Grok Bot does an outstanding job of resear..."

Billy Howell

Inference disaggregation partnership to increase total throughput

"We're doing disaggregation with AMD and with AWS, where you think about in the work of inference, is there a part that can be done by somebody else and is there a part that can be done by you. We're seeing similar numbers with AWS."

Andrew Feldman

Cloud infrastructure for SaaS application

"We had no idea about AWS as it relates to like app usage. So like our early day bills on AWS and like the first time we set up Snowflake were like crazy high."

Zach Cherin

Voice cloning clients' voices to produce podcast content in multiple languages (including Spanish), dubbing videos into 13 languages

"Because of ElevenLabs — have you heard of that? I use it to dub all my videos. This video will be in 13 different languages in our clone voices. I take his script, I clone his voice. Now he reads it perfectly in any language we want. I mix the jingle on the..."

Mike Stewart

Transcribing voice recordings from Plaud for use as AI prompts

"I use ElevenLabs for transcription. They're probably the best speech-to-text model."

Lex Fridman