Methylone
A psychoactive empathogenic compound described as a shorter-acting, lower-body-load cousin of MDMA, being commercialized by Transcend Therapeutics for therapeutic use.
Recently discussed in
How Methylone compares
3 creators weighed in
M
MDMA
Direct rival
classic therapeutic empathogen drug
Methylone is shorter (45-60 min vs 4-6 hrs) and gentler, with less body load and less serotonin depletion, making weekly dosing possible.
K
3 creators
K
3 creators
Methylone is shorter (45-60 min vs 4-6 hrs) and gentler, with less body load and less serotonin depletion, making weekly dosing possible.
"I had my first methylone experience probably 2015... an incredibly beautiful gentle experience, and maybe the soft-spoken, shorter-staying cousin of MDMA. So rather than coming in and you're like, when's this guy gonna leave, six hours, ..."
Softer and shorter-acting than MDMA
"What most people didn't realize at the time is that it has some advantages over MDMA... You can take methylone once a week in our trials. You actually can't take MDMA once a week. It's a little bit more toxic. It depletes your serotonin ..."
Compared to MDMA
"Methylone is, for lack of a better descriptor, it's like the softer, gentler cousin of MDMA who just comes in for a quick hello as opposed to sitting down for dinner. It's like a 45 to 60 minute hello as opposed to 4 to 6 hours."
Compared to MDMA as a shorter, gentler alternative
"Methylone is a very, very interesting compound. It's like the shorter acting, softer cousin of MDMA — much less body load. Very, very interesting compound. They did, which was very smart, they just completely separated the two and actual..."
Compared to MDMA as a softer, shorter-acting alternative
What creators say
"I had my first methylone experience probably 2015... an incredibly beautiful gentle experience, and maybe the soft-spoken, shorter-staying cousin of MDMA. So rather than coming in and you're like, when's this guy gonna leave, six hours, it's more ..."
More from Tim Ferriss →+1 more mention from Tim
"Methylone is, for lack of a better descriptor, it's like the softer, gentler cousin of MDMA who just comes in for a quick hello as opposed to sitti..."
"What most people didn't realize at the time is that it has some advantages over MDMA... You can take methylone once a week in our trials. You actually can't take MDMA once a week. It's a little bit more toxic. It depletes your serotonin a little b..."
More from Kevin Ryan →"Methylone is a very, very interesting compound. It's like the shorter acting, softer cousin of MDMA — much less body load. Very, very interesting compound. They did, which was very smart, they just completely separated the two and actually removed..."
More from Andrew Huberman →Keep exploring
Topics
About this data
- ✓44,000+ mentions extracted from real podcast transcripts
- ✓Every quote links to the source episode
- ✓Sponsored mentions are always labeled
- ✓Critical takes are shown, never filtered out