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GLP-1 agonists
Class of medications originally developed for diabetes that also promote weight loss and may reduce cravings for various substances including alcohol.
medication
diabetes
weight loss
addiction treatment
pharmaceuticals
neuroprotection
insulin resistance
weight management
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"This is where the GLP-1s actually I think are super super valuable because this is a problem of insulin resistance. The GLP ones break this insulin resistance. They also break food noise."
From:
What Every Woman MUST KNOW About Midlife Hormonal Changes | Gynecologic Oncologist Elizabeth Poynor
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▶ 1:12:31
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Jan 2026
Attribution: Elizabeth Poynor recommends GLP-1 agonists for midlife women struggling with insulin resistance and weight management despite doing everything right with lifestyle
"I'm extremely interested in them. their effects on substance use. My patients desire is they want not to want. So, which is different than like I want to conquer my desire. Like, I just wish I didn't desire this drug as much as I do"
From:
How to Overcome Addiction to Substances or Behaviors | Dr. Keith Humphreys
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▶ 2:20:35
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Jan 2026
Attribution: Humphreys expresses strong interest in GLP-1s for addiction treatment and is actively working on research in this area
"I look at the potential around GLP-1 agonist and I look at the ways that we're getting better understanding of hormones"
Attribution: Peter Attia mentions GLP-1 agonists as part of promising treatments he's optimistic about