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Dr. Keith Humphreys
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Vicodin
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"I had to take Vicodin for the pain afterwards. I find taking opioids so unpleasant. I feel bound up, you know, miserable, groggy that I just took one and said, 'Pain is better than this.'"
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"I had to take Vicodin for the pain afterwards. I find taking opioids so unpleasant. I feel bound up, you know, miserable, groggy that I just took one and said, 'Pain is better than this.'"
"There's a model called Oxford House which is run by the people who live there and they all contribute a bit to the rent and have a recovery culture. Those kind of things have really good evidence of benefit."
"There's a tremendous book Addiction by Design and I'm afraid I'm going to mispronounce the name of the person who wrote I think it's Schull but I'm not sure but I know the title Addiction by Design about gambling"
"you want to stop drinking, I would, you know, suggest go check into an AA meeting or one of the other fellowships we have. Having other people on the same journey is good for us."
From:
How to Overcome Addiction to Substances or Behaviors | Dr. Keith Humphreys
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▶ 0:31
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Jan 2026
"That is the only thing that really looks good for stimulant use disorder. You can do it under insurance coverage now in most places."
"I'd be far more likely to actually do the same protocol that Nolan Williams developed with RTMS because the effects of that for treatment resistant depression are so much clearer in my view and the downsides are far as I can see virtually nil."
"People would come in five days in a row and have 10 minutes on, 50 minutes off all day long, 5 days, at a theta burst setting for the RTMS. I've seen some people's lives just absolutely changed by that."
"I'm extremely interested in them. their effects on substance use. My patients desire is they want not to want. So, which is different than like I want to conquer my desire. Like, I just wish I didn't desire this drug as much as I do"
"me John Kelly and Mara Ferry did what's called a Cochrane collaboration review this is the creme de la creme most rigorous review of evidence in medicine"
"There's lots of people who benefit from SSRI. There's no question. SSRIs have been very very helpful to the community of people who suffer from true OCD."
"It is FDA approved for treatment resistant depression. There are some positive trials and I know a couple people who said it was very valuable to them in a deep depression but I didn't view it as quite the knockout I thought it was going to be."
"there's also like smart recovery and women for sobriety"
"there's also like smart recovery and women for sobriety"
"particularly with semaglutide which is the GLP that is in Wegovy and Ozempic"
"particularly with semaglutide which is the GLP that is in Wegovy and Ozempic and alcohol drops in alcohol use"