Episodes featuring a16z
Browse episodes where a16z appears as host or guest. View all episodes →
Amjad Masad (Replit) and Alex Atallah (Open Router) argue that specialized, focused AI models will outperform general-purpose models for most enterprise use cases.
Vladimir Keil of LEO talks with a16z about how AI agents are taking over complex enterprise procurement, from negotiation to contracts, in ways legacy software cannot.
Barrett Lyon, who built early DDoS and CDN infrastructure, explains why the internet's original model broke and how his new project Docset aims to restore privacy through decentralized networking.
A16z partners Sarah Wang, Alex Immerman, and Santiago Rodriguez discuss the macro trends behind tech's current investment boom, from hyperscaler spending to early enterprise AI adoption.
a16z and David Pawlan discuss what makes AI personal agents worth paying for, covering specialization, proactivity, and how agents could reshape commerce.
Diogo Almeida, founder of Typesafe, talks with a16z about why AI automation has largely failed and how his tool Jev embeds decision-making directly inside software.
Aaron Levie, Steven Sinofsky, and Martin Casado debate AI safety messaging, regulation, and where innovation is actually heading as big labs lose their grip.
a16z partners Josh Elman, Olivia Moore, and David Booth discuss Cosign, a platform that surfaces peer endorsements to help founders and investors find exceptional talent before the broader market does.
Replit CEO Amjad Masad joins a16z and Gagan Biyani to discuss why traditional college fails young people and what a better two-year exploratory program could look like in the AI era.
Ben Horowitz, Gagan Biyani, and Erik Torenberg discuss a new academy in San Francisco built to train entrepreneurs for the AI era, rejecting the traditional college model.
Steve Stoute and a16z's Ben Horowitz discuss the Paid in Full Foundation, which gives multi-year financial grants to hip-hop pioneers who built a trillion-dollar culture but received almost nothing from it.
Databricks CEO Ali Ghodsi talks with a16z about why AI existential risk messaging is overblown and what enterprises should actually focus on to get value from AI.
Gorkem Yurtseven and Batuhan Taskaya of Fal explain how post-training optimization of the open-source Minimax H3 model achieved 35x speed improvements and 2x cost reductions in AI video generation.
Keith Peiris, CEO of Lightfield, explains how his company rebuilds CRM from scratch for AI-era startups, replacing manual data entry and rigid fields with automatic capture of customer interactions.
Ruby Justice Thelot and a16z explore how internet culture turns niche health trends like GLP-1 peptides into viral obsessions, and what that gap between hype and real adoption means for builders.
OpenAI President Greg Brockman joins a16z to discuss why he believes we have entered the AGI era and what businesses and governments should do about security and access to AI.
a16z investors David George and Aram Verdiyan explain how AI is reshaping venture capital, from portfolio construction to which fund sizes and strategies can still deliver strong returns.
a16z and Rayan Krishnan discuss why independent AI evaluation has become critical infrastructure, covering how enterprises pick models, measure ROI, and verify safety claims.
OpenAI researchers Mehtaab Sawhney and Mark Sellke discuss how AI models are achieving breakthroughs in pure mathematics by exploring solution spaces and executing complex proofs without the cognitive limits humans face.
A16z talks with World Labs co-founders Justin Johnson and Fei-Fei Li about Atlas, a world model that unifies 3D reconstruction and generation using next-view prediction.