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D-cycloserine

product

2 creators use or recommend it

▲ 1 active in the last 90 days

2 use
Last discussed Oct 18, 2026

An antibiotic that acts as a catalyst for neuroplasticity when used with TMS treatments.

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Andrew Huberman and Tim Ferriss use or recommend D-cycloserine. See what else they have in common.

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How D-cycloserine compares

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P
Psychedelics Different focus
mind-altering hallucinogenic substances

Tim says D-cycloserine is a small antibiotic dose that induces brain plasticity similarly to psychedelics, but without the mind-altering effects.

1 creator
Tim Ferriss

"You're doing one day of treatment accelerated with this very small dose of antibiotic called D-Cycloserine, which induces plasticity in the brain much like certain psychedelics. So you basically let that dissolve in your mouth beforehand."

Compared to psychedelics

What creators say

Used for: Inducing brain plasticity before neuromodulation treatment Praised: Induces plasticity much like certain psychedelics vs: Compared to psychedelics

"You're doing one day of treatment accelerated with this very small dose of antibiotic called D-Cycloserine, which induces plasticity in the brain much like certain psychedelics. So you basically let that dissolve in your mouth beforehand."

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+2 more mentions from Tim

"I predosed with something called D-cycloserine. And I did one day and Dan this time around boom it was just like a switch basically the next day."

"I predosed with something called D-cycloserine. This little drug is a catalyst for neuroplasticity."

Used for: Priming neuroplasticity before accelerated TMS to compress multi-day protocols into a single session Praised: Allows 5-day TMS protocol to be compressed into one day; enhances neuroplasti... vs: Compared to standard 5-day TMS protocols and 3-6 month traditional TMS protocols

"Using an agent, in this case an antibiotic, to induce neuroplasticity called D-cycloserine. You take — the most common dose is 125 milligrams, oral, and you dissolve it an hour before your stimulation. You take that five-day protocol and compress ..."

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