Episodes featuring Y Combinator
Browse episodes where Y Combinator appears as host or guest. View all episodes →
BillionToOne Is Solving One of Biotech’s Hardest Problems
BillionToOne has cracked one of biotech's hardest problems: detecting rare genetic signals in blood samples by solving a "needle in a haystack" challenge of finding one abno...
François Chollet: Why Scaling Alone Isn’t Enough for AGI
François Chollet, creator of Keras and founder of NDIA (a new AGI research lab), argues that scaling alone is insufficient for achieving AGI and proposes an alternat...
Inside The Startup Reinventing America’s Trillion Dollar Chemical Industry
This Y Combinator episode features Solugen, a Houston-based startup reinventing chemical manufacturing by combining enzymatic biology with metal catalysts to produce ind...
India’s Fastest Growing AI Startup
Emergent founders Makund and Madav Jha discuss how their AI coding agent platform has reached 7 million apps built in just 8 months, making it one of Y Combinator's fastest-...
The Future Of Brain-Computer Interfaces
Max Hodak, co-founder of Neuralink and founder of Science, discusses the transformative potential of brain-computer interfaces (BCIs) to restore lost sensory and motor funct...
Common Mistakes With Vibe Coded Websites
Y Combinator partners review landing pages built with AI design tools, analyzing common mistakes and best practices for startup websites. The episode examines how AI-assiste...
The Powerful Alternative To Fine-Tuning
Ian Fischer, co-founder of Poetic, discusses a paradigm shift beyond fine-tuning: building recursively self-improving AI reasoning harnesses that automatically optimize ...
The AI Agent Economy Is Here
Y Combinator hosts discuss how AI agents are becoming independent economic actors reshaping software markets and startup strategy. The hosts argue that **AGI is functionally...
Inside Claude Code With Its Creator Boris Cherny
Boris Cherny, creator of Claude Code, discusses how he built a terminal-based AI coding agent that has dramatically increased developer productivity at Anthropic and beyond....