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Leucovorin

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Last discussed Jan 15, 2026

A medication that provides folate to the body, used as a treatment that bypasses blocked folate receptors to allow methylated folate to cross the blood-brain barrier.

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MM
Marty Makary
mentioned

"They have observed that if you give leucovorin as an example which bypasses the blocked receptor allowing methylated folate to get into the blood-brain barrier they have seen clinical improvement."

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