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Marty Makary
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Everything Marty personally uses, recommends, or has created — plus things they don't recommend — sourced from their own show and appearances on other podcasts.
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Froot Loops
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"Froot Loops was making cereal for Canada where the petroleum based dyes were banned and a different Froot Loops for the United States for American kids."
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"We're going to get that down to one day. We're going to use AI."
"We have organ on a chip technology where you grow say the liver cells or heart cells in a lab administer the drug and then look for any enzyme leaks or disturbances. These are modern techniques."
"We have computational modeling now. Computer can look at a drug and actually make better predictions"
"We are now going to allow Bayesian statistics to be used. So now you can if something works instead of having a committee meet twice a year to do a cut of the data"
"I believe in both the letter and the spirit of right to try. It's an amazing achievement of President Trump in his first term and I have signed 100% of right to try requests that come across my desk."
"CAR-T is amazing. I'm not here to promote any one class of drugs but I mean the stuff that we have seen is mind-boggling."
"GLP-1s are mimicking a natural hormone in the body. And so when you get a supplementation of that, it's doing the job of increasing satiety, slowing down GI motility"
"They have observed that if you give leucovorin as an example which bypasses the blocked receptor allowing methylated folate to get into the blood-brain barrier they have seen clinical improvement."
"Sometimes the studies are not reproducible in JAMA, our most widely circulated medical journal, a randomized trial giving a protease to kids with autism and noticing an improvement."
"A treatment came out for a certain type of congenital deafness. It's a gene therapy device combination. It came out in the New England Journal of Medicine."
"Froot Loops was making cereal for Canada where the petroleum based dyes were banned and a different Froot Loops for the United States for American kids."