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technique
Five R Program
1 creator use or recommend it
▲ 1 active in the last 90 days
1 use + recommend
Last discussed Sep 7, 2026
A functional medicine gut-healing framework consisting of five steps: Remove, Replace, Reinoculate, Repair, and Restore — used to systematically address gut dysfunction.
Recently discussed in
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Mark Hyman, MD · Sep 7, 2026
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Mark Hyman, MD · Sep 2, 2026
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What creators say
Mark Hyman, MD
uses
recommends
Used for: Resetting gut health for patients with SIBO, dysbiosis, leaky gut, and related conditions
Praised: Used clinically with thousands of patients; addresses root causes across five...
"We have a whole system that we've developed that's based on a framework called the five R program, essentially to reset the gut — which is remove the bad stuff like allergens or bad bugs or SIBO or parasites; replace what's missing, which could be..."
More from Mark Hyman, MD →+1 more mention from Mark
"In functional medicine, we call it the Five R Program. Remove, replace, reinoculate, repair, and restore. An elimination diet plus a five R gut res..."
The Perfect Gut Healing Protocol: What to Eat, Avoid, and...
· Jun 22, 2026
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