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DAO (Diamine Oxidase)
1 recommend
Last discussed Jul 13, 2026
A digestive enzyme supplement that degrades histamine in the gut, taken before meals to reduce food-derived histamine reactions.
Recently discussed in
Your Doctor Can't Find What's Wrong? It Might Be MCAS
Mark Hyman, MD · Jul 13, 2026
What creators say
Mark Hyman, MD
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Used for: Degrading histamine in the gut before meals to reduce food-derived histamine reactions
Praised: Directly degrades histamine in the gut
"You can also take DAO as a supplement. DAO is diamine oxidase. It's an enzyme that degrades histamine in the gut. You take it before meals when food-derived histamine might be a problem."
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