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Calorie-Restricted Mediterranean Diet

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Last discussed Jul 16, 2026

A dietary pattern emphasizing fish (salmon, sardines), olive oil, avocado, and vegetables with overall caloric restriction, used as an alternative to strict ketogenic diets for managing cancer metabolically.

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Thomas Seyfried
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Used for: Managing glioblastoma and potentially other cancers by keeping blood sugar low and elevating ketones through plant- and fish-based whole foods with caloric restriction Praised: Clinically validated in glioblastoma patients, achieves low GKI without stric... vs: Presented as an alternative to the carnivore/ribeye approach and strict ketog...

"Our group in Greece got tremendous success in keeping glioblastoma patients alive. What was the diet? It was a calorie-restricted Mediterranean diet — salmon, sardines, olive oil, avocado, and exercise."

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