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Calcium channel blockers
Last discussed Sep 7, 2026
A class of medications that relax blood vessels and reduce heart rate by blocking calcium from entering heart and blood vessel muscle cells, used to treat hypertension.
Recently discussed in
Blood pressure: how to measure, manage, and treat high blood pressure (AMA #48 rebroadcast)
Peter Attia · Sep 7, 2026
What creators say
Peter Attia
mentioned
Used for: Add-on blood pressure treatment; may be preferred in African-American patients
Praised: High efficacy (~15 mmHg systolic reduction)
vs: More side effects than ACE inhibitors/ARBs; used as add-on rather than first-...
"Calcium channel blockers are also highly efficacious. Those are easily in the 15 mm of mercury impact on blood pressure, but they do tend to come with more side effects. We typically do not like to rely on those as first-line agents."
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