Siddhartha Mukherjee

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"Losartan or whatever ACE inhibitor or ARB inhibits your capacity to have high blood pressure by acting on your kidneys' hormonal system."

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"Aspirin is a key. We know the lock. Lipitor is a key. We know the lock. Prozac is a key. We know the lock."

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"Two good examples are the use of a drug called Enhertu in breast cancer, which works even after many, many lines of therapies have stopped working."

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"You've seen cases of pancreatic cancer treated with daraxonrasib, a new medicine against one of those killer genes called Ras. It's extended the life of patients."

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"After painting the back with this chemical carcinogen, they added an inflammatory agent, croton oil. Something that you can buy from Amazon. And all of a sudden 80 cancers grew."

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"This has been a great success in leukemias, B cell leukemias and B cell lymphomas, producing not just small cures, but durable cures. Just as a plug for one of the things I do, I created one of the first CAR-T cell companies in India, where we sell the therapy for 1/20th the price that's available in the United States."

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"We have some tools. We have the GLP-1s, for instance. In obesity and potentially in inflammation, so that's a trial that I would like to watch very, very carefully."

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"That's standard immunotherapy. Keytruda is one example of that. There are other ones."

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"I think that it's possible using all these technologies including what we're developing and including CRISPR to really think about eliminating some global infectious diseases."

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"Antibodies for instance like Herceptin which is for breast cancer"

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"Rituximab which is for lymphoma and others that you might be taking for asthma or other diseases"

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"But putting in random stuff, metformin... that's just a mess."