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Ropinirole

product
Last discussed Aug 24, 2026

A dopamine agonist medication that acts directly on dopamine D2 and D3 receptors, used to treat Parkinson's disease and restless legs syndrome.

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MH
Masud Husain
mentioned
Used for: Restoring motivation in patients with basal ganglia lesions causing pathological apathy Praised: Directly stimulates dopamine D2/D3 receptors; dramatically restored motivatio... vs: Compared to L-dopa which made no difference; ropinirole acts directly on rece...

"This drug, ropinirole, latches onto dopamine receptors directly and stimulates the dopamine circuitry. Three months after we started this medication, David came back to see us — he'd had a shower, a haircut, he was wearing a suit, he had a new job..."

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