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PREEMPT Protocol

technique
Last discussed Aug 31, 2026

The standardized injection protocol for Botox (onabotulinumtoxinA) for chronic migraine prevention, involving injections at 31 sites across the forehead, sides and back of the head, neck, and shoulders every 12 weeks.

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BG
Brian Grosberg
mentioned
Used for: Standardized Botox administration for chronic migraine prevention

"The protocol went through a number of iterations until the current protocol, which is called the PREEMPT protocol, which is standard across the world, where injections are given in the forehead, on the sides of the head, the back of the head, the ..."

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