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GnRH Agonist

product

1 creator use or recommend it

1 recommend
Last discussed Jun 22, 2026

A class of medications (e.g., leuprolide, goserelin) that initially stimulate then suppress GnRH receptors, leading to profound suppression of estrogen production, used to treat endometriosis and adenomyosis.

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RT
Renato Tomioka
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Used for: Pre-embryo transfer hormonal suppression in adenomyosis patients to improve implantation rates and reduce miscarriage Praised: More data available than oral antagonists, lower cost than oral antagonists vs: Compared to oral GnRH antagonists (Elagolix, Relugolix) — similar efficacy, m...

"We prefer the GnRH agonist. Two to four months of this and then we transfer the embryo using tiny levels of estrogen and high amounts of progesterone. We have much more data with the agonists."

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