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DNA methylation clock

technique
Last discussed Apr 16, 2026

Biological aging measurement test that analyzes methylation patterns in DNA to determine biological age versus chronological age.

What creators say

David Sinclair
mentioned
Used for: Measuring biological aging rate and tracking intervention effects Praised: Developed by Steve Horvath, people with slower clocks tend to live longer and... vs: Association never conclusive in science, but good correlation with longevity

"You can measure the rate of aging by looking at how these methyls change over time. It's called a DNA methylation clock if you want to look it up. I would say that there's not one clock to rule them all."

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