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Dapsone

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1 creator use or recommend it

▲ 1 active in the last 90 days

1 recommend
Last discussed Jul 29, 2026

An antibiotic and anti-inflammatory drug originally used for leprosy and dermatitis herpetiformis, now used by Dr. Horowitz in a combination protocol for treating chronic Lyme disease as a biofilm persister drug.

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RH
Richard Horowitz
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Used for: 9-week combination antibiotic protocol targeting biofilm persister bacteria in chronic Lyme disease; also used for Alzheimer's neuroinflammation prevention Praised: Great CNS penetration; blocks NLRP3 inflammasomes; antimalarial properties; b... vs: Replaced long-term IV antibiotics which Horowitz no longer uses; superior to ...

"I published my first article in 2016 on 100 patients on low-dose Dapsone — fatigue got better, joint pain got better, neuropathy got better, brain fog, headaches. I tweaked the protocol over the last 10 years and got it down to 8 to 9 weeks. It do..."

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