Episodes featuring This Week in Startups

3D-Printed Homes for $99K: ICON’s Jason Ballard on the future of housing | E2277

Jason Ballard, founder of ICON, discusses how 3D-printed concrete homes can solve the housing crisis while simultaneously serving military defense and space exploration ...

This 22-Year-Old Built TikTok for Mobile Games, and It’s Growing Fast | E2276

Two 22- and 24-year-old founders have built Nanog, a TikTok-style feed for casual mobile games where users can play dozens of games per session and create new ones using AI ...

Bittensor’s (alleged) $10M rug pull (feat. Mark Jeffrey) | E2275

This episode explores Bittensor, a decentralized AI network attempting to democratize frontier model training, but is dominated by discussion of a major ecosystem failure: s...

Bittensor Drama! TAO down 15%! | E2274

This episode explores the recent Bittensor governance crisis where a prominent subnet founder allegedly mishandled tokens, causing TAO to drop 15%, and examines why dece...

Anthropic’s Mythos is a cyber-weapon, so you can’t have it | E2273

Anthropic's new Mythos model is so powerful at finding and exploiting software vulnerabilities that the company refuses to release it publicly, treating it as a potential cy...

3 AI Agents That Actually Replaced Human Jobs | E2272

This episode explores three AI agents that are actually replacing human jobs and discusses the economic implications of agentic AI. The hosts and guests—including founders build...

AI Rebuilt Every YC W26 Startup. Should Founders Be Scared? | E2271

This episode examines whether AI can replicate startup ideas by showcasing FeltSense, a company that used autonomous AI agents to rebuild every Y Combinator W26 batch compan...

Venture Roundtable: SpaceX IPO, AI's PR Crisis, and the Defense Tech Bubble | E2270

This roundtable discussion covers three major narratives shaping tech and venture in 2026: SpaceX's imminent IPO targeting a June launch (potentially the largest IPO ever), ...

The 5-Step Framework for AI Agents That Improve While You Sleep | E2269

This episode presents Shubham Saboo's five-step framework for building autonomous AI agents that improve and operate independently, demonstrated through his team of six ...

The $60 billion resource hiding in space, and the start trying to mine it | E2268

Jason Calacanis hosts three fascinating guests exploring the cutting edge of space mining, decentralized AI training, and AI-powered meeting assistants. The episode showcases ho...

This Bittensor Subnet Could Cut Drug Discovery Costs in HALF | E2267

This episode explores three different Bittensor subnets that demonstrate the versatility of decentralized AI incentive networks for solving real-world problems. Hosts Alex a...

32 Million Dollar Fraud? Delve Scandal | E2266

This episode examines the Delve fraud scandal, where a YC-backed compliance automation startup allegedly generated fake SOC 2 reports for enterprise clients, raising cri...

The Drone Company Everyone Thought Was Illegal (Now Worth $4B+) | E2265

This episode features Keller Clifton, founder of Zipline, discussing how the drone delivery company overcame initial skepticism to become a $4B+ valued company deliv...

How Robinhood became a $68B company w/ Vlad Tenev

Jason Calacanis interviews Robinhood co-founder Vlad Tenev about how the company grew from a zero-revenue idea to a $68 billion company by democratizing stock trading on mob...

Are Brain-Computer Interfaces Actually Ready for Humans? | E2263

This episode features three interviews with founders building transformative hardware and health technologies. Alex Carp discusses brain-computer interfaces with Paradromics...

One Genius Rule That Made This Coffee Brand Famous | EP 2262

This episode features two distinct segments: first, a deep dive into Bit Tensor and Hippius Subnet 75, a decentralized, blockchain-powered cloud storage platform designe...

The Global Expansion of Self-Driving Vehicles

This Week in Startup's panel discussion examines the current state and near-future of autonomous vehicles, featuring executives from Autolane, Edge Case, and Move wh...

How agents will change banking forever | E2260

This episode explores how AI agents are fundamentally transforming banking, business automation, and employment while highlighting a stark divide in how different countries ...

Wisdom of the $TAO: the future is decentralized AI

This episode explores decentralized AI through the lens of BitTensor and TAO, a blockchain-based system that incentivizes distributed AI development through mining r...

Is Anthropic Making the Biggest Mistake in AI History? | E2258

This episode discusses the explosive growth of OpenClaw, an open-source AI project that has become the most-starred project in GitHub history, and explores its implications ...